diff --git a/matrix-synapse.spec b/matrix-synapse.spec
index 4c1994c..f705829 100644
--- a/matrix-synapse.spec
+++ b/matrix-synapse.spec
@@ -3,8 +3,6 @@
 # Version suffix in URL when building release candidates
 %global rcx %{nil}
 
-%{?python_enable_dependency_generator}
-
 Name:       matrix-%{srcname}
 Version:    1.57.0
 Release:    1%{?dist}
@@ -18,56 +16,8 @@ Source3:    matrix-synapse.sysusers
 BuildArch:  noarch
 
 BuildRequires:  python3-devel
-BuildRequires:  python3-setuptools
-
-# Test dependencies
-BuildRequires:  python3-parameterized >= 0.7.0
 BuildRequires:  /usr/bin/openssl
-
-# Package dependencies
-#BuildRequires:  python3-txacme >= 0.9.2
-BuildRequires:  (python3-attrs >= 19.2.0 without python3-attrs = 21.1.0)
-BuildRequires:  python3-authlib
-BuildRequires:  python3-bcrypt >= 3.1.0
-BuildRequires:  python3-bleach >= 1.4.3
-BuildRequires:  python3-canonicaljson >= 1.4.0
-BuildRequires:  python3-cryptography >= 3.4.7
-BuildRequires:  (python3-frozendict without python3-frozendict = 2.1.2)
-BuildRequires:  python3-idna >= 2.5
-BuildRequires:  python3-ijson
-BuildRequires:  python3-jinja2
-BuildRequires:  python3-jsonschema
-BuildRequires:  python3-jwt
-BuildRequires:  python3-lxml
-BuildRequires:  python3-matrix-common
-BuildRequires:  python3-matrix-synapse-ldap3 >= 0.1
-BuildRequires:  python3-msgpack >= 0.5.2
-BuildRequires:  python3-netaddr >= 0.7.18
-BuildRequires:  python3-packaging >= 16.1
-BuildRequires:  python3-phonenumbers >= 8.2.0
-BuildRequires:  python3-pillow
-BuildRequires:  python3-prometheus_client
-BuildRequires:  python3-pyOpenSSL >= 16.0.0
-BuildRequires:  python3-pyasn1 >= 0.1.9
-BuildRequires:  python3-pyasn1-modules >= 0.0.7
-BuildRequires:  python3-pymacaroons-pynacl >= 0.13.0
-BuildRequires:  python3-pynacl >= 1.2.1
-BuildRequires:  python3-pysaml2 >= 4.5.0
-BuildRequires:  python3-pyyaml >= 3.11
-BuildRequires:  python3-service-identity >= 18.1.0
-BuildRequires:  python3-signedjson >= 1.1.0
-BuildRequires:  python3-sortedcontainers >= 1.4.4
-BuildRequires:  python3-systemd >= 231
-BuildRequires:  python3-treq >= 15.1
-BuildRequires:  python3-twisted >= 18.9.0
-BuildRequires:  python3-typing-extensions
-BuildRequires:  python3-unpaddedbase64 >= 1.1.0
-BuildRequires:  systemd
-BuildRequires:  xmlsec1
-
-Requires(pre):  shadow-utils
-Requires:       systemd
-%{?systemd_requires}
+BuildRequires:  systemd-rpm-macros
 
 %description
 Matrix is an ambitious new ecosystem for open federated Instant Messaging and
@@ -85,12 +35,17 @@ the ecosystem.
 rm -rf synapse/static
 
 
+%generate_buildrequires
+%pyproject_buildrequires -x test,systemd
+
+
 %build
-%py3_build
+%pyproject_wheel
 
 
 %install
-%py3_install
+%pyproject_install
+%pyproject_save_files %{srcname}
 
 # Synapse includes some benchmarks in a separate Python package named "synmark"
 # which is installed by default. Remove it to avoid shipping it in the Fedora
@@ -111,22 +66,23 @@ PYTHONPATH=. trial-3 tests
 %pre
 %sysusers_create_compat %{SOURCE3}
 
+
 %post
 %systemd_post synapse.service
 
+
 %preun
 %systemd_preun synapse.service
 
+
 %postun
 %systemd_postun_with_restart synapse.service
 
 
-%files
+%files -f %{pyproject_files}
 %license LICENSE
 %doc *.rst
 %config(noreplace) %{_sysconfdir}/sysconfig/synapse
-%{python3_sitelib}/synapse/
-%{python3_sitelib}/matrix_synapse*.egg-info/
 %{_bindir}/*
 %{_unitdir}/synapse.service
 %attr(755,synapse,synapse) %dir %{_sharedstatedir}/synapse